Are you highly motivated and data-driven with a passion for oncological drug development?

Want A Role with Impact?

Join us to develop breakthrough clinical interventions for patients with cancer through targeted radiotherapeutics and radiodiagnostics.

Our Team: Solve Therapeutics, Inc. is a US-based biotechnology company developing antibody-drug conjugates (ADC) and antibody-radionuclide conjugates (ARC) to treat life-threatening cancers. We have research facilities in both San Diego, CA, and Durham, NC. Our leadership comprises a highly experienced biotechnology team with a strong track record of success with startup companies and in developing clinical drugs.

We are currently expanding our ARC research and development at the Durham, North Carolina site and are seeking a full-time Nuclear Medicine Biochemist to join our team.

Here’s What You’ll Do.

• You will join a research team developing a preclinical pipeline focused on both radionuclide therapeutics and companion diagnostics for ADCs.
• Research responsibilities for this role will focus on the radiolabeling of antibodies and biological ligands with radionuclides, overseeing the subsequent protein characterization and cellular bioactivity assays of the targeted radiotherapeutics.
• You will have a central role in progressing and expanding the preclinical portfolio of radiotherapeutics and radio diagnostics for oncology.

It’s All About You.

• You have 2-4+ years of Radionuclide expertise (critical to this role).
• You are highly reliable, self-motivated, team-centric, and adaptable to the flexibility required in biotechnology start-up companies.
• You have strong analytical, data management, and communication skills.

Education Requirements: MS or PhD highly preferred

Technical Skills – Highly Desired

• Radiolabeling chemistry (halogen and metal)
• Antibody bioconjugation chemistry
• PET radio diagnostics labeling
• Protein analytical techniques

• SDS polyacrylamide electrophoresis, ELISA assays, Lindmo assay, HPLC)

• Cellular bioactivity assays
• Affinity, internalization, & cytotoxicity assays
• Cell culture
• Radionuclide handling expertise

Desired, but not necessary

• Surface Plasmon Resonance (SPR)
• Flow Cytometry
• VHH, sdAb, or mAb drug conjugate development experience
• Protein mass spectrometry
• PET and/or SPECT imaging and analysis
• Recombinant protein engineering & expression (E.coli or mammalian)
• Animal tumor models

Compensation: This position is a full-time position with a base salary commensurate with your educational level, skill set, and experience. The position includes full medical benefits and the potential for an annual bonus and stock-option equity.

Don’t meet every requirement listed? Studies show that women and people of color are less likely to apply for jobs when they don’t meet every requirement. At Solve Therapeutics, we are committed to building a diverse and inclusive community, so if you think you could crush this role, even without all the listed qualifications, please apply!

Solve Therapeutics is proud to be an equal opportunity employer and consider qualified applicants without regard to race, color, religion, sex, national origin, ancestry, age, genetic information, sexual orientation, gender identity, marital or family status, veteran status, medical condition, or disability.