Job description
Job Description
POSITION OBJECTIVE
Working under moderate supervision, the Research Assistant 1 will perform research experiments in medical and related technical areas. The research assistant will maintain specialized knockout and transgenic mice uniquely developed in the lab for studies in basic immunology. The research assistant will also perform basic immunology experiments to look at inflammatory molecules in order to discover underlying pathogenic mechanisms that cause chronic intestinal inflammation, such as that observed in patients with inflammatory bowel disease. This position will work with animals.
ESSENTIAL FUNCTIONS
- Perform research work in medical and related technical areas involves use of lab skills. Maintain, organize, and perform minor husbandry of animal colonies. This includes but is not limited to providing care for animals, inspecting animals regularly, maintaining ID/records of all animals, and keeping datasheets up-to-date and circulated appropriately. Requires extensive and delicate handling of animals. (25%)
- Conduct analysis of samples. These include measurements of inflammatory molecules at the gene levels (by quantitative polymerase chain reaction experiments) and at the protein levels (by Western blot experiments, enzyme-linked immunosorbent assay; ELISA, or immunohistochemistry techniques). (20%)
- Maintain test equipment utilized in experiments. Aid in managing samples, including tissue and biological fluid (i.e., blood) collection, processing and accurately recording data associated with samples and research. (15%)
- Record results for a particular experiment or closely related series of experiments by using software, such as Graphpad Prism, or Excel. (15%)
- Maintain records of experiments. Keep detailed and organized records of experiments, protocols and procedures, and laboratory equipment utilized in experiments and the collected data. Organize shipment of samples from or to the laboratory. Maintain certification and servicing of laboratory equipment. (10%)
- Order general laboratory supplies and maintain inventory. (10%)
NONESSENTIAL FUNCTIONS
- Prepare solutions, buffers, and media for use in experiments as needed. (5%)
- Perform other assigned duties. Interact with the administrative office or other departments for issues regarding safety, budget, purchase orders and department organization. (<1%)
CONTACTS
Department: Frequent contact with supervisor to discuss research and maintain workflow. Frequent contact with lab colleagues to discuss research and maintain workflow.
University: Occasional contact with other departments to share information.
External: Occasional contact with vendors to exchange information.
Students: Occasional Contact with student employees to exchange information.
SUPERVISORY RESPONSIBILITY
This position has no direct supervision of staff employees.
QUALIFICATIONS
Education/Experience: Bachelor’s degree in science and 0 to 1 year of experience or Associate's degree in an approved biotechnology program and 0 to 2 years of experience required.
REQUIRED SKILLS
- Experience with proper animal handling and husbandry.
- Familiarity with safe handling of biohazardous materials (human blood and body fluids); and knowledge of safe handling practices for laboratory chemicals.
- Experience with basic laboratory equipment (centrifuge, light microscopes, balances, pH meter, incubators, etc.) and ability to learn new techniques and procedures as needed.
- Ability to closely follow established protocols or laboratory procedures and request clarification if necessary
- Exceptional organizational skills in record-keeping with ability to organize, and accurately document data. Must have the ability to maintain meticulous, complete, and easily retrievable laboratory and clinical data.
- Verbal and written communication skills to be effective in communicating and interacting with a diverse group of people within a laboratory setting and a hospital setting. Ability to interact with colleagues, supervisors, and patients face to face.
- Experience in use of computers and software including MS Word, Excel, PowerPoint, and Outlook.
- Must demonstrate effective time management skills and ability to meet consistent attendance.
- Must demonstrate compliance with university animal research and care (ARC) policies and procedures and compliance to regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines and other applicable regulatory guidelines.
- Must demonstrate compassion for animals within university facilities and dedication to the Animal Resource Center’s mission. Must handle animals with care and respect at all times.
- Must be able and willing to maintain a high standard of personal cleanliness and utilize protective gear to protect the health of the animals.
- Previous experience working with animals preferred.
- Ability to work with sensitive information and maintain confidentiality.
- Ability to meet consistent attendance.
WORKING CONDITIONS
General laboratory and office environments. May have exposure to hazards. Frequently required to use appropriate gloves and personal protective equipment. In rare cases, may be requested to work overtime and weekends for experiments. The research assistant will receive proper biohazard and general lab safety training, as well as training for lab specific safety measures.
Case Western Reserve University's animal facilities are accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC) and is managed according to the "Guide for the Care and Use of Laboratory Animals” appropriate Federal Animal Welfare Regulations, and the Public Health Service “Policy on the Humane Care and Use of Laboratory Animals." This position, and all animal research personnel, are subject to internal compliance to SOM Animal Resource Center Standard Operating Procedures and to compliance regulations of the Animal Welfare Act, Public Health Service Policy, AAALAC guidelines, the State of Ohio Veterinary Practice Act, Federal Drug Enforcement Administration regulatory guidelines, US Food and Drug Administration Center for Veterinary Medicine regulations and other applicable regulatory guidelines.
Diversity Statement
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
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Reasonable Accommodations
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Equity at 216-368-3066 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.
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COVID Vaccination
Case Western Reserve University has implemented a COVID Vaccination policy requiring evidence of COVID-19 vaccination for all students, faculty and staff with an on-campus presence. Religious and medical exemptions may be provided in accordance with applicable federal and state laws. For more information go to: https://case.edu/equity/covid-19-accommodations. Applicants may contact the Office of Equity at 216-368-3066 /equity@case.edu for information regarding religious or medical exemptions as an accommodation.
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