Job description
About Loxo@Lilly:
Loxo@Lilly aims to create medicines that make life better for all those affected by cancer around the world. Bringing together the focus and spirit of a biotech with the scale, resources, and heritage of Lilly, our team is focused on rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating oncology medicines that unequivocally show early signs of clinical activity and will matter to patients. We intend to curate a balanced pipeline of medicines, either internally or externally discovered, with the potential to treat cancer with dramatic effect. Loxo@Lilly was created in December 2019, combining the Lilly Oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. Loxo@Lilly is a global organization with team members in Louisville, Colorado; Indianapolis, Indiana; New York City, New York; San Diego, California; South San Francisco, California; Stamford, Connecticut; and Madrid, Spain.
Loxo@Lilly's newly formed Drug Discovery group in Louisville, Colorado has an immediate opening for a researcher in Biophysics. The Loxo Drug Discovery group’s mission is to invent life-changing targeted therapies for cancer patient populations that are poorly treated by existing therapies. To that end, we are building a multi-disciplinary team of dedicated drug discovery scientists who are passionate about driving the science forward to create highly selective drugs for known oncogenic drivers.
The ideal candidate is self-motivated, responsible, and a productive scientist who enjoys collaborating with biologists, chemists, and assay scientists. In this role, he/she will utilize a variety of assay technologies including mass spectrometry, fluorescence spectroscopy, surface plasmon resonance, and isothermal titration calorimetry to evaluate protein/ligand interactions. Experience in protein purification and characterization is a plus. This position requires excellent people skills, a positive can-do attitude, passion for lab work, attention to detail, and the ability to thrive in a highly interactive, fast-paced, team environment.
Roles and Responsibilities of the Position
- Prosecute biophysical assays to identify and characterize small-molecule modulators using a variety of techniques and detection methods, including chromogenic, MS, SPR, ITC, FP, FRET and TR-FRET
- Continuously expand our biochemical characterization repertoire by exploring and developing additional assay and technological instrumentation
- Calculate and report assay results to the project teams
- Document experiments and results in electronic notebook, and results database
Required Qualifications and Preferred Background
- A BS or MS with 0-3+ years relevant work experience. Level commensurate with education and experience
- Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels
- Highly organized and detail oriented with excellent analytical, documentation, and multi-tasking skills
- Committed continual learner, who is accustomed to staying current with the latest scientific breakthroughs in structure-based drug design and biophysics
- Expertise in other methods of enzymology or biophysical characterization and structural biology is a plus
- Protein Purification and characterization a plus
Loxo@Lilly currently anticipates that the base salary for the Lead Specialist level position could range from between $57,500 to $77,000 and that the base salary for the Scientist could range from between $61,500 to $90,200 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. This position will also be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Loxo provides a comprehensive benefit program to eligible employees, including vacation, medical, dental and vision benefits; participation in a 401(k) plan; life and accidental death and disability coverage; parental leave benefits and employee discounts for certain items. The compensation described above is subject to change and could be higher or lower than the range described.
Physical Demands/Travel:
The physical demands of this position are consistent with working in a laboratory/ bench environment. Some lifting, and maneuvering of equipment may be required.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position’s work environment is based in a laboratory/ bench environment.
The work environment characteristics described here are representative of those an employee encounters while preforming the essential functions of this job.
- To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Loxo@Lilly (Eli Lilly and Company) is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).
Loxo@Lilly (Eli Lilly and Company) is committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Loxo, please email loxoaccommodation@loxooncology.com
for further assistance. Please note, this email address is intended for use to request an accommodation as a part of the application process. Any other correspondence will not receive a response.
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