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The Tumor Microenvironment Thematic Research Center (TME TRC) at Bristol Myers Squibb is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to immune checkpoint blockade and targeted therapies and transforming response and durability rates for cancer patients. Comprising of scientists across multiple disciplines, we are responsible for the biology and translational science required to support drug development from target identification through to first in human studies.

Position Summary:

We are seeking a highly motivated and experienced Senior Scientist with oncology drug discovery and development experience to join the Stromal Biology team as part of the Immunology and Stromal Biology Discovery group within the TME TRC (Redwood City, CA). The individual will drive early drug discovery programs across both large and small molecules from target identification through target validation and lead optimization and, ultimately, toward clinical proof of concept in patients. The individual will work collaboratively with drug discovery, predictive science, translational and clinical teams to advance molecules and build a deeper understanding of the role for stromal/vascular biology in the TME. The qualified candidate will bring extensive knowledge in oncology, drug development, stromal and/or endothelial biology to the team.

Position Responsibilities:

In the role as a Senior Scientist within the TME TRC Stromal Biology team, the ideal candidate:

• Biology Program Lead for endothelial/vascular discovery portfolio projects across large and small molecule therapeutic modalities

• Design and execution of robust preclinical data packages to support drug discovery programs

• Contribution to exploratory target identification and validation of novel targets

• Participation in review of external/business development opportunities

• Biology discovery support for vascular facing clinical assets

• Opportunities to formulate and guide strategies for endothelial targeting in the TME

Experience =

Basic Qualifications:

• Bachelor’s Degree

  • 7+ years of academic and / or industry experience

Or

• Master’s Degree

  • 5+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences

  • 2+ of academic and / or industry experience

Preferred Qualifications:

• PhD with 2+ years of relevant experience, M.S. with 8-10 years of relevant industry experience, or B.S. with 12-15 years of relevant industry experience

• Proven track record in cancer biology, immuno-oncology, and/or stromal/vascular/endothelial biology demonstrated by academic and/or patent publications.

• Strong background in biologics and/or small molecule drug discovery, including the ability to design and execute a strategy to validate and optimize drug candidates.

• Knowledge of in vivo or in vitro preclinical models to assess endothelial biology and its contribution to oncology or immunology is highly desirable.

• Experience with multi-color flow cytometry for immune cell profiling

• Understanding of vascular normalization, endothelial interactions with TME, and relevant endothelial model systems

• In vivo and in vitro pre-clinical modeling of therapeutic antibodies or small molecules.

The starting compensation for this job is a range from $109,000.00 – $150,700.00, plus incentive cash and stock opportunities (based on eligibility).

The starting pay rate takes into account characteristics of the job, such as required skills and where the job is performed.

Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit our BMS Career Site.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick
time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

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If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

COVID-19 Information
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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