The Position

Genentech seeks a computational chemist with strong experience in structure-based drug design, ligand-based design, and cheminformatics to join our Computational Drug Discovery group in the Discovery Chemistry Department. You will be an integral member of interdisciplinary drug discovery project teams, where you will apply computational chemistry, cheminformatics, machine learning, and artificial intelligence to help drive lead discovery, optimization, and development. You will work closely with Medicinal Chemistry, Structural Biology, Biochemistry, DMPK, and other functional areas.

You will have access to state of the art modeling, simulation, and machine learning technologies as well as computing infrastructure, and be able to leverage rich collections of data to accelerate drug discovery in a fast-paced and creative environment. Based at our beautiful South San Francisco campus, you will join a team that is leveraging computation to discover new medicines to address unmet medical needs. This is a tremendous opportunity to do meaningful work in an exciting, dynamic environment.

Who You Are

• Ph.D. or equivalent in Chemistry, Biochemistry, Biophysics, or other related discipline

• Significant experience in computational chemistry, structure and ligand based design, modeling, and experience designing molecules with medicinal chemists is required

• Excellent interpersonal, verbal, and written communication skills and the ability to work collaboratively in teams

• Practical, working experience with computational chemistry software from companies such as Chemical Computing Group, Schrodinger, OpenEye, Gaussian, and Dotmatics

• Knowledge of machine learning, deep learning, and scientific scripting (e.g. Python) is desirable

• 8+ years of Industry experience in small molecule drug discovery

Relocation benefits are available for this position

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The expected salary range for this position based on the primary location of California is 170,500.00 and 316,600.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

Genentech requires all new hires to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Genentech, and it applies regardless of whether the position is located at a Genentech campus or is fully remote. If you are unable to receive the vaccine due to a disability or serious medical condition, or because it is prohibited as a result of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation.