Do you have expertise and scientific reputation in the Metabolic and Liver Diseases research area? Are you excited by a role where you will provide global scientific leadership within your area of expertise to accelerate innovative science and turn ideas into life changing medicines? Would you like to apply your expertise in a company where we work together across boundaries to make the impossible a reality? Join us to be part of the discovery of future treatments for Cardiovascular, Renal and Metabolic diseases

We are now recruiting a Scientific Leader in Metabolic and Liver Diseases to Early Cardiovascular, Renal and Metabolism (Early CVRM), one of AstraZeneca’s three main therapeutic areas. Within Early CVRM, novel ideas for drugs are to be discovered and developed in a cross-functional and collaborative environment to meet unmet medical needs for patients. As the Scientific Leader you will be a key player in the global CVRM community with opportunity to directly influence Early CVRM science and capabilities to ensure cutting-edge scientific leadership both today and in the future. You will have the opportunity to work at the forefront of cardiovascular, renal and metabolic research and continue to demonstrate scientific leadership through high quality publications, conference presentations and by building networks and collaborations with key opinion leaders and academic groups.

The role will be placed at AstraZeneca’s dynamic R&D site in Gaithersburg, MD. Here you will be part of an international, open-minded and creative working atmosphere based on collaboration and innovation. The role is at a Senior Director level, commensurate with your level of experience and qualifications for the role. You will report to the Head of Bioscience Metabolism.

Main Duties and Responsibilities

With your entrepreneurial mindset you are open to challenges and thrive on innovative ways of working to achieve scientific excellence and progression of a rich and diverse pipeline of both small and large molecules including several novel modalities.

Your responsibilities will include:

• Provide scientific expertise into the Metabolism and Liver Disease research area to drive the development and progression of a portfolio of pre-clinical and early clinical opportunities to support Early CVRM in achieving its business objectives and the delivery of the CVRM strategy.

• As a senior leader based at the Gaithersburg site, provide mentorship and represent CVRM to site and CVRM leadership teams.

• Take on a discipline accountability role in pre-clinical and clinical project teams.

• Keep up to date with the latest advances in metabolic disease research to achieve scientific excellence at all levels ensuring that highest quality research is carried out.

• Apply scientific leadership across our CVRM indications where applicable Raise the visibility and profile of CVRM within and outside AstraZeneca.

• Build and maintain a network to key internal and external stakeholders and leading research institutions.

• Share responsibility and contribute with knowledge and expertise to impact delivery of disease area strategy and business plan for Early CVRM to ensure excellence in CVRM delivery of valuable new medicines.

• Collaborate closely and be the interphase to other essential functions in the drug development process, both inside and outside of Early CVRM e.g.

• Bioscience Cardiovascular, Bioscience Renal, Translational Science, DMPK, Early Clinical development, Chemistry, Discovery Sciences, Clinical Pharmacology & Safety Sciences and Precision Medicine.

Requirements

• The right person has a PhD and post-doctoral experience in the areas of e.g. Diabetes, Obesity, NASH, Dyslipidemia or equivalent.

• A broad and solid understanding of the Metabolic Diseases Therapeutic Area including relevant pre-clinical in vitro and in vivo models in combination with a solid understanding of physiology and pharmacology.

• You are an internationally recognised scientist with entrepreneurial and innovation driven leadership abilities together with a strong publication track record. With your excellent inter-personal skills and genuine openness to novel scientific approaches you are able to build successful internal/external partnership and collaboration relationships while demonstrating cultural sensitivity and awareness.

• It is essential that you are comfortable in the interaction with senior leaders and have the ability to influence and operate effectively in a global multidisciplinary matrix research environment to provide global scientific leadership and insight in drug discovery.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next!

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you